TL;DR for Decision-Makers
Panama does not issue a dedicated crypto licence. You operate through a Sociedad Anónima (or SFI / Foundation) registered with the Public Registry, plus an AML/CFT framework aligned with Law 23 of 2015 and UAF expectations. No minimum capital, no pre-approval permit, and 0% tax on foreign-sourced income under Panama’s territorial system. Setup runs 3–6 weeks end-to-end — incorporation in 2–3 weeks, AML build in parallel, bank or EMI onboarding 2–4 weeks. Total fixed-fee budget with Fintech Simple starts at €4,500. The trade-off versus EU MiCA: faster and cheaper, no passport into the EU; you pick the tool that fits the market you serve.